Synthesis of Brominated Quercetin Derivatives Using Distinct Brominating Systems

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Synthesis, characterization and cytotoxicity of alkylated quercetin derivatives

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Quercetin, a ubiquitous flavonol, represents a promising leading drug for development of new chemotherapeutic agents. However, its limited cytotoxicity to cancer cells hampers its clinical use. In order to obtain novel quercetin derivatives with superior cytotoxicity, seven alkylated quercetin derivatives were synthesized. Solubility of these derivatives was determined by turbidimetry. Cytotoxi...

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quercetin, a ubiquitous flavonol, represents a promising leading drug for development of new chemotherapeutic agents. however, its limited cytotoxicity to cancer cells hampers its clinical use. in order to obtain novel quercetin derivatives with superior cytotoxicity, seven alkylated quercetin derivatives were synthesized. solubility of these derivatives was determined by turbidimetry. cytotoxi...

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ژورنال

عنوان ژورنال: Asian Journal of Chemistry

سال: 2014

ISSN: 0970-7077,0975-427X

DOI: 10.14233/ajchem.2014.16175